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Last Updated: October 26, 2021

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Patent: 6,087,129

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Summary for Patent: 6,087,129
Title: Recombinant expression of proteins from secretory cell lines
Abstract:The present invention a provides methods for production of heterologous polypeptides using a variety recombinantly engineered secretory cell lines. The common feature of these cell lines is the absence of expression of at least one endogenous polypeptide. The host cell machinery normally used to produce the endogenous polypeptide is then usurped for the purpose of making the heterologous polypeptide. Also described are methods engineering cells for high level expression, methods of large scale protein production, and methods for treatment of disease in vivo using viral delivery systems and recombinant cell lines.
Inventor(s): Newgard; Christopher B. (Dallas, TX), Normington; Karl D. (Dallas, TX), Clark; Samuel A. (Rockwall, TX), Thigpen; Anice E. (Dallas, TX), Quaade; Christian (Dallas, TX), Kruse; Fred (Dallas, TX)
Assignee: Betagene, Inc. (Dallas, TX) Board of Regents, The University of Texas System (Austin, TX)
Application Number:08/589,028
Patent Claims:see list of patent claims

Details for Patent 6,087,129

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 1974-01-15 ⤷  Free Forever Trial 2039-02-26
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 1984-12-27 ⤷  Free Forever Trial 2039-02-26
Ferring Pharmaceuticals Inc. NOVAREL chorionic gonadotropin For Injection 017016 1985-02-15 ⤷  Free Forever Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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