➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

AstraZeneca
Medtronic
Boehringer Ingelheim
McKesson
Merck
Moodys

Last Updated: September 29, 2020

DrugPatentWatch Database Preview

Patent: 6,071,517

➤ Get the DrugPatentWatch Daily Briefing
» See Plans and Pricing

« Back to Dashboard

Summary for Patent: 6,071,517
Title: Bispecific heteroantibodies with dual effector functions
Abstract:Bispecific molecules which react both with the high-affinity Fc.gamma. receptor of human effector cells and with a target cell surface antigen are disclosed. Binding of the molecules to the Fc receptors found on effector cells is not blocked by human immunoglobulin G. The molecules are useful for targeting human effector cells (e.g. macrophages) against cells bearing the target antigen. For this purpose, bispecific molecules can be constructed containing the binding region derived from an anti-Fc.gamma. receptor antibody and the binding region derived from an antibody specific for the target antigen. Targeted effector cells can be used to destroy cells bearing the target cell surface antigen by cell-mediated antibody dependent cytolysis and by complement-fixation.
Inventor(s): Fanger; Michael W. (Lebanon, NH), Guyre; Paul M. (Hanover, NH), Ball; Edward D. (Norwich, VT)
Assignee: Medarex, Inc. (NJ)
Application Number:08/359,931
Patent Claims:see list of patent claims

Details for Patent 6,071,517

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Csl Behring Ag CARIMUNE human immunoglobulin g INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 102367 1 2009-02-10   Start Trial Medarex, Inc. (NJ) 2017-06-06 search
Csl Behring Ag PRIVIGEN human immunoglobulin g LIQUID 125201 1 2009-01-20   Start Trial Medarex, Inc. (NJ) 2017-06-06 search
Bio Products Laboratory Limited GAMMAPLEX human immunoglobulin g SOLUTION 125329 1 2017-04-07   Start Trial Medarex, Inc. (NJ) 2017-06-06 search
Csl Behring Ag HIZENTRA human immunoglobulin g LIQUID 125350 1 2020-01-01   Start Trial Medarex, Inc. (NJ) 2017-06-06 search
Adma Biologics, Inc. ASCENIV human immunoglobulin g LIQUID 125590 1 2019-04-01   Start Trial Medarex, Inc. (NJ) 2017-06-06 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Baxter
Mallinckrodt
Dow
Moodys
McKinsey

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.