Modified amino acids and compositions comprising the same for delivering active agents
The present invention provides modified amino acids for delivering active agents, and particularly biologically or chemically active agents. The preferred modified amino acids of the present invention include N-acylated or sulfonated amino acids. These modified amino acids are used as carriers to facilitate the delivery of a cargo to a target. Such modified amino acids are well suited to form non-covalent mixtures with biologically-active agents for oral administration to animals. Methods for the preparation and administration of the modified amino acids and compositions including the same are also provided.
Leone-Bay; Andrea (Ridgefield, CT), Ho; Koc-Kan (Mt. Kisco, NY), Press; Jeffery Bruce (Brewster, NY), Wang; Nai-Fang (Long Island, NY)
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