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Last Updated: January 26, 2020

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Patent: 6,057,298

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Summary for Patent: 6,057,298
Title: Keratin K1 expression vectors and methods of use
Abstract:A keratin K1 vector for expression of a nucleic acid sequence in an epidermal cell. The vector includes a 5\' flanking region which includes necessary sequences for expression of a nucleic acid cassette, a keratin K1 3\' flanking region which regulates expression of a nucleic acid sequence, predominantly in the epidermis, and a linker which connects the 5\' flanking region to a nucleic acid. The linker has a position for inserting a nucleic acid cassette. The linker does not contain the coding sequence of a gene that the linker is naturally associated with. That is, the linker is not the normal gene associated with the 5\' and 3\' regions.
Inventor(s): Roop; Dennis R. (Houston, TX), Rothnagel; Joseph A. (Houston, TX), Greenhalgh; David A. (Houston, TX), Yuspa; Stuart H. (Bethesda, MD)
Assignee: Baylor College of Medicine (Houston, TX) The United States of America as represented by the Department of Health (Washington, DC)
Application Number:08/452,872
Patent Claims:see list of patent claims

Details for Patent 6,057,298

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Baylor College of Medicine (Houston, TX) The United States of America as represented by the Department of Health (Washington, DC) 2017-05-02 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Baylor College of Medicine (Houston, TX) The United States of America as represented by the Department of Health (Washington, DC) 2017-05-02 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Baylor College of Medicine (Houston, TX) The United States of America as represented by the Department of Health (Washington, DC) 2017-05-02 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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