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Boehringer Ingelheim

Last Updated: February 17, 2020

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Patent: 6,015,713

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Summary for Patent: 6,015,713
Title: Transgenic fish and a method of harvesting islet cells therefrom
Abstract:This invention relates to transgenic fish containing a humanized insulin gene which has been altered to secrete human insulin and its use in the treatment of diabetes. In the transgenic fish of the present invention, the fish insulin gene has been modified to code for human insulin gene while leaving the regulatory sequences of fish insulin gene intact. Islet transplantation may provide the meticulous glycemia control required in the treatment of diabetes. The islet tissue of the present invention offers an inexpensive and a nearly unlimited supply of human insulin-producing tissue and therefore, may be useful in the treatment of diabetes. In this regard, an improved method of mass isolation of islet tissue is provided by the present invention. The present invention also provides the use of the humanized insulin gene to promote growth in fish.
Inventor(s): Wright, Jr.; James R. (Halifax, CA), Pohajdak; Bill (Dartmouth, CA)
Assignee: Dalhousie University (Nova Scotia, CA)
Application Number:08/750,391
Patent Claims:see list of patent claims

Details for Patent 6,015,713

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Dalhousie University (Nova Scotia, CA) 2015-04-06 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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