Compositions and methods for diagnosis of mutation in the von Hippel-Lindau tumor suppressor gene
The instant invention relates to methods and products for the diagnosis of mutations in the von Hippel-Lindau tumor suppressor gene. More specifically, the products are DNA oligonucleotides for use in amplifying and sequencing genomic DNA and kits including these oligonucleotides. The method of the invention relates to a hierarchical system for cost-effective diagnosis of von Hippel-Lindau tumor suppressor disease-associated mutations.
Hui; May (Toronto, CA), Dunn; James M. (Scarborough, CA), Stevens; John K. (Toronto, CA), Capatos; Denis (Waterloo, CA), Matthews; David E. (Kitchener, CA)
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