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Last Updated: November 28, 2021

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Patent: 6,008,436

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Summary for Patent: 6,008,436
Title: Nematode-resistant transgenic plants
Abstract:Nematode-resistant transgenic plants are disclosed. The plants comprise plant cells containing a DNA construct comprising a transcription cassette, which construct comprises, in the 5\' to 3\' direction, a promoter operable in the plant cells, and a DNA comprising at least a portion of a DNA sequence encoding a nematode-inducible transmembrane pore protein in either the sense or antisense orientation. Intermediates for producing the same along with methods of making and using the same are also disclosed. In an alternate embodiment of the invention, the sense or antisense DNA is replaced with a DNA encoding an enzymatic RNA molecule directed against the mRNA transcript of a DNA sequence encoding a nematode-inducible transmembrane pore protein.
Inventor(s): Conkling; Mark A. (Fuquay-Varina, NC), Opperman; Charles H. (Raleigh, NC), Acedo; Gregoria N. (Durham, NC), Song; Wen (Raleigh, NC)
Assignee: North Carolina State University (Raleigh, NC)
Application Number:08/654,025
Patent Claims:see list of patent claims

Details for Patent 6,008,436

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2013-01-21
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2013-01-21
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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