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Last Updated: October 18, 2021

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Patent: 5,942,496

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Summary for Patent: 5,942,496
Title: Methods and compositions for multiple gene transfer into bone cells
Abstract:Disclosed are methods, compositions, kits and devices for use in transferring nucleic acids into bone cells in situ and/or for stimulating bone progenitor cells. Type II collagen and, particularly, osteotropic genes, are shown to stimulate bone progenitor cells and to promote bone growth, repair and regeneration in vivo. Gene transfer protocols are disclosed for use in transferring various nucleic acid materials into bone, as may be used in treating various bone-related diseases and defects including fractures, osteoporosis, osteogenesis imperfecta and in connection with bone implants.
Inventor(s): Bonadio; Jeffrey (Ann Harbor, MI), Goldstein; Steven A. (Ann Harbor, MI)
Assignee: The Regent of The University of Michigan (Ann Arbor, MI)
Application Number:08/316,650
Patent Claims:see list of patent claims

Details for Patent 5,942,496

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 2015-01-23 ⤷  Free Forever Trial The Regent of The University of Michigan (Ann Arbor, MI) 2016-08-24 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 5,942,496

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 9522611 ⤷  Free Forever Trial
World Intellectual Property Organization (WIPO) 9738729 ⤷  Free Forever Trial
United States of America 2002193338 ⤷  Free Forever Trial
United States of America 2010189792 ⤷  Free Forever Trial
United States of America 2012100107 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Harvard Business School
Johnson and Johnson

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