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Generated: September 24, 2019

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Patent: 5,942,496

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Summary for Patent: 5,942,496
Title: Methods and compositions for multiple gene transfer into bone cells
Abstract:Disclosed are methods, compositions, kits and devices for use in transferring nucleic acids into bone cells in situ and/or for stimulating bone progenitor cells. Type II collagen and, particularly, osteotropic genes, are shown to stimulate bone progenitor cells and to promote bone growth, repair and regeneration in vivo. Gene transfer protocols are disclosed for use in transferring various nucleic acid materials into bone, as may be used in treating various bone-related diseases and defects including fractures, osteoporosis, osteogenesis imperfecta and in connection with bone implants.
Inventor(s): Bonadio; Jeffrey (Ann Harbor, MI), Goldstein; Steven A. (Ann Harbor, MI)
Assignee: The Regent of The University of Michigan (Ann Arbor, MI)
Application Number:08/316,650
Patent Claims:see list of patent claims

Details for Patent 5,942,496

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Try a Free Trial The Regent of The University of Michigan (Ann Arbor, MI) 2016-08-24 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Try a Free Trial The Regent of The University of Michigan (Ann Arbor, MI) 2016-08-24 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Try a Free Trial The Regent of The University of Michigan (Ann Arbor, MI) 2016-08-24 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Try a Free Trial The Regent of The University of Michigan (Ann Arbor, MI) 2016-08-24 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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