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Last Updated: September 30, 2020

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Patent: 5,919,703

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Summary for Patent: 5,919,703
Title: Preparation and storage of pancreatic islets
Abstract:A method, a solution and a chamber for the preparation and storage of pancreatic islets. The method includes contacting a pancreas with a warm collagenase solution, digesting the pancreas in the warm collagenase solution to form warm digest, adding cold preservative solution to the warm digest, agitating the warm digest/cold preservative solution at a temperature between about 0.degree. and 15.degree. C., to thereby further digest the partially digested pancreas included in the warm digest, to form cold digest and collecting liquid from the cold digest to form isolated islets. The cold preservative solution and a pancreatic islet preservative solution of the present invention include D-mannitol, K-lactobionate and a buffer.
Inventor(s): Mullen; Yoko (Sherman Oaks, CA), Kenmochi; Takashi (Hanamigawaku, JP)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:08/660,746
Patent Claims:see list of patent claims

Details for Patent 5,919,703

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial The Regents of the University of California (Oakland, CA) 2015-04-10 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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