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Last Updated: November 29, 2021

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Patent: 5,919,703

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Summary for Patent: 5,919,703
Title: Preparation and storage of pancreatic islets
Abstract:A method, a solution and a chamber for the preparation and storage of pancreatic islets. The method includes contacting a pancreas with a warm collagenase solution, digesting the pancreas in the warm collagenase solution to form warm digest, adding cold preservative solution to the warm digest, agitating the warm digest/cold preservative solution at a temperature between about 0.degree. and 15.degree. C., to thereby further digest the partially digested pancreas included in the warm digest, to form cold digest and collecting liquid from the cold digest to form isolated islets. The cold preservative solution and a pancreatic islet preservative solution of the present invention include D-mannitol, K-lactobionate and a buffer.
Inventor(s): Mullen; Yoko (Sherman Oaks, CA), Kenmochi; Takashi (Hanamigawaku, JP)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:08/660,746
Patent Claims:see list of patent claims

Details for Patent 5,919,703

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2015-04-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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