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Generated: September 23, 2019

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Patent: 5,891,671

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Summary for Patent: 5,891,671
Title: Method for cleaving chimeric protein using processing enzyme
Abstract:A chimeric protein is provided which comprises a target protein and has been designed so as to be easily cleaved by a processing enzyme, permitting a target protein to be efficiently recovered. The chimeric protein is represented by the following formula: wherein A represents a protective peptide; B represents a target peptide; and L represents a linker peptide having the sequence X.sub.1 -X.sub.2 -(Pro, Lys, or Arg)-Arg, wherein X.sub.1 and X.sub.2 represent any amino acid, in its C-terminal region and a domain rich in His in its N-terminal region.
Inventor(s): Suzuki; Yuji (Ashikaga, JP), Magota; Koji (Takatsuki, JP), Masuda; Toyofumi (Ibaraki, JP)
Assignee: Suntory Limited (Osaka, JP)
Application Number:08/811,028
Patent Claims:see list of patent claims

Details for Patent 5,891,671

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23 ➤ Sign Up Suntory Limited (Osaka, JP) 2016-03-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23 ➤ Sign Up Suntory Limited (Osaka, JP) 2016-03-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23 ➤ Sign Up Suntory Limited (Osaka, JP) 2016-03-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23 ➤ Sign Up Suntory Limited (Osaka, JP) 2016-03-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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