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Last Updated: June 3, 2020

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Patent: 5,880,255

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Summary for Patent: 5,880,255
Title: Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct of PEG and granulocyte-macrophage colony stimulating factor
Abstract:The invention relates to fractionating a mixture of polyethylene glycol (PEG)-protein adducts having different degrees of PEG substitution by partitioning the PEG-protein adducts in a PEG-containing aqueous biphasic system according to the degree of PEG substitution. A new PEG-gm-CSF obtained by the process is useful in pharmaceutical compositions for use in therapeutic or diagnostic methods.
Inventor(s): Delgado; Cristina (London, GB), Francis; Gillian Elizabeth (London, GB), Fisher; Derek (London, GB)
Assignee: PolyMASC Pharmaceuticals plc (London, GB2)
Application Number:08/422,992
Patent Claims:see list of patent claims

Details for Patent 5,880,255

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial PolyMASC Pharmaceuticals plc (London, GB2) 2016-03-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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