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Patent: 5,874,479
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Summary for Patent: 5,874,479
| Title: | Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same |
| Abstract: | This invention pertains to therapeutic wound healing compositions for protecting and resuscitating mammalian cells (Embodiment One (I)). This invention also pertains to therapeutic permeation enhanced-wound healing compositions for enhancing the penetration of actives into membranes and increasing the proliferation and resuscitation rate of mammalian cells (Embodiment Two (II)). In a first aspect of Embodiment One (I.A), the therapeutic wound healing composition comprises (a) pyruvate, (b) an antioxidant, and (c) a mixture of saturated and unsaturated fatty acids. In a second aspect of Embodiment One (I.B), the therapeutic wound healing composition comprises (a) pyruvate, (b) lactate, and (c) a mixture of saturated and unsaturated fatty acids. In a third aspect of Embodiment One (I.C), the therapeutic wound healing composition comprises (a) an antioxidant and (b) a mixture of saturated and unsaturated fatty acids. In a fourth aspect of Embodiment One (I.D), the therapeutic wound healing composition comprises (a) lactate, (b) an antioxidant, and (c) a mixture of saturated and unsaturated fatty acids. In Embodiment Two (II), the therapeutic wound healing compositions of Embodiment One (I.A-D) are combined with a therapeutically effective amount of a permeation enhancing agent (PE) to form permeation enhanced-wound healing compositions (II.A-D+PE). This invention also pertains to methods for preparing and using the permeation enhanced-wound healing compositions and the topical and ingestible pharmaceutical products in which the therapeutic compositions may be used. |
| Inventor(s): | Martin; Alain (Ringoes, NJ) |
| Assignee: | Warner-Lambert Company (Morris Plains, NJ) |
| Application Number: | |
| Patent Claims: | see list of patent claims |
Details for Patent 5,874,479
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Interferon Sciences | ALFERON N INJECTION | interferon alfa-n3 | VIAL | 103158 | 001 | 1989-10-10 | Start Trial | Warner-Lambert Company (Morris Plains, NJ) | 2017-02-06 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 5,874,479
| Country | Patent Number | Publication Date |
|---|---|---|
| South Africa | 9201538 | Nov 25, 1992 |
| South Africa | 9209155 | May 25, 1993 |
| South Africa | 9301297 | Jun 27, 1994 |
| >Country | >Patent Number | >Publication Date |
