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Last Updated: September 27, 2020

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Patent: 5,869,127

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Summary for Patent: 5,869,127
Title: Method of providing a substrate with a bio-active/biocompatible coating
Abstract:Disclosed is a method of enhancing the biocompatibility of a substrate by providing the substrate with a continuous bio-active surface coating. This method includes applying to the substrate a first coating which includes an aqueous dispersion or emulsion of a polymer containing an organic acid functional group and an excess of a polyfunctional cross-linking agent which is reactive with the organic acid groups of the polymer. A continuous bio-active surface coating is then formed over the dried first coating by applying thereover a bio-active agent containing an organic acid functional group or metal salt thereof. The first and second coatings are then dried to covalently bond the organic acid functional groups of the bio-active agent to the polymer through the excess unreacted polyfunctional cross-linking agent.
Inventor(s): Zhong; Sheng-Ping (Northboro, MA)
Assignee: Boston Scientific Corporation (Natick, MA)
Application Number:08/877,825
Patent Claims:see list of patent claims

Details for Patent 5,869,127

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial Boston Scientific Corporation (Natick, MA) 2015-02-22 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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