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Last Updated: September 22, 2020

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Patent: 5,859,311

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Summary for Patent: 5,859,311
Title: Transgenic mice which overexpress neurotrophin-3 (NT-3) and methods of use
Abstract:Transgenic mice express increased levels of neurotrophin-3 (NT-3) in epithelium when their ancestors are microinjected with the NT-3 gene. The NT-3 growth factor expressing transgenic mice are useful in the study of neurodegenerative disorders of the brain such as Parkinson\'s syndrome and Alzheimer\'s disease, of the spinal cord motor neurons such as amyotrophic lateral sclerosis, and for testing drug candidates for the treatment of these diseases.
Inventor(s): Albers; Kathryn M. (Lexington, KY), Davis; Brian M. (Lexington, KY)
Assignee: University of Kentucky Research Foundation (Lexington, KY)
Application Number:08/534,685
Patent Claims:see list of patent claims

Details for Patent 5,859,311

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial University of Kentucky Research Foundation (Lexington, KY) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial University of Kentucky Research Foundation (Lexington, KY) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial University of Kentucky Research Foundation (Lexington, KY) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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