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Last Updated: December 5, 2021

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Patent: 5,827,703

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Summary for Patent: 5,827,703
Title: Methods and composition for in vivo gene therapy
Abstract:Novel methods and compositions are provided for introducing a gene capable of modulating the genotype and phenotype into two or more tissues following systemic administration. The gene can be introduced into a mammalian host by way of an expression vector either as naked DNA or complexed to lipid carriers, particularly cationic lipid carriers. Multiple individual tissues can be transfected using naked DNA. Using a DNA: lipid carrier complex, multiple tissues and cell types can be transfected. The techniques and compositions find use in the palliation or treatment of any of a variety of genetic-based disorders.
Inventor(s): Debs; Robert James (Mill Valley, CA), Zhu; Ning (El Cerrito, CA)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:08/246,376
Patent Claims:see list of patent claims

Details for Patent 5,827,703

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2015-10-27
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2015-10-27
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Colorcon
Medtronic
Merck
Moodys
McKinsey
Express Scripts

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