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Last Updated: September 19, 2020

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Patent: 5,817,473

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Summary for Patent: 5,817,473
Title: Method and device for identifying a mycobacterium species responsible for a mycobacterial infection
Abstract:A method for identifying a Mycobacterium species responsible for a mycobacterial infection in human or animal, comprising selecting a suitable mycobacterial species and strain; preparing at least one mycobacterial antigen, respectively antigen preparation; binding the antigen, respectively the antigen preparation to a suitable carrier, causing the binding antigen to react with antibodies from serum of an individual infected with a Mycobacterium species; making visible antigen-antibody reactions for a suitable antibody (sub-)class; and identifying the responsible Mycobacterium on the basis of the reactions which are made visible. The invention further provides a diagnostic kit which takes the form of a dip-stick on which is arranged a carrier strip with mycobacterial antigens binding thereto, and visualizing reagents antigen-antibody reactions occurring on the carrier after contact with the serum for testing. In another embodiment, the diagnostic kit comprises a micro titer plate, in the wells of which a specified antibody is arranged, and reagents for making visible antigen-antibody reactions occurring in the wells after contact with the serum for testing. The third embodiment is an immunoblot with mycobacterial antigens separated by electrophoresis binding thereto, and reagents for visualizing antigen-antibody reactions occurring on the immunoblot after contact with the serum for testing.
Inventor(s): Das; Pranab Khumar (Castricum, NL), Van Es; Remco Maria (Koog aan de Zaan, NL), Houthoff; Hendrik Jan (Amsterdam, NL)
Assignee: Kreatech Biotechnology B.V. (Ez Amsterdam, NL)
Application Number:08/454,122
Patent Claims:see list of patent claims

Details for Patent 5,817,473

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Organon Usa Inc. TICE BCG bacillus calmette-guerin POWDER, FOR SUSPENSION 102821 1 1990-08-24   Start Trial Kreatech Biotechnology B.V. (Ez Amsterdam, NL) 2012-12-17 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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