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Last Updated: December 5, 2021

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Patent: 5,807,823

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Summary for Patent: 5,807,823
Title: Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
Abstract:Synthetic polypeptide analogs of parathyroid hormone PTH, parathyroid hormone related peptide PTHrp, and of the physiologically active truncated homologs and analogs of PTH and PTHrp, in which amino acid residues (22-31) form an amphipathic .alpha.-helix, said residues (22-31) selected from hydrophilic amino acids (Haa) and lipophilic amino acids (Laa) ordered in the sequence: and their pharmaceutically acceptable salts are useful for the prophylaxis and treatment of ostoporosis in mammals. Processes for the production of the polypeptides via solid phase and recombinant methods are provided.
Inventor(s): Krstenansky; John L. (Palo Alto, CA), Nestor; John J. (Cupertino, CA), Vickery; Brian H. (Mountain View, CA)
Assignee: Syntex (U.S.A.) Inc. (Palo Alto, CA)
Application Number:08/449,317
Patent Claims:see list of patent claims

Details for Patent 5,807,823

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Try it Free 2015-09-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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