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Last Updated: September 29, 2020

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Patent: 5,804,694

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Summary for Patent: 5,804,694
Title: Commercial production of .beta.-glucuronidase in plants
Abstract:A method for commercial production of GUS entails heterologous expression of the protein in plants, in native conformation, at an expression level such that avidin represents at least 0.1% of total extracted protein. A genetic map of the integration locus allows for the identification of the GUS-expressing plant. Genetic loci on a plant chromosome are revealed that support high levels of GUS expression and that can be used as a site of integration for high level expression of other genes of interest.
Inventor(s): Bruce; Wesley B. (Urbandale, IA), Hood; Elizabeth (Clive, IA), Peterson; David J. (Ames, IA), Register, III; James C. (Ames, IA), Witcher; Derrick (Urbandale, IA), Howard; John A. (West Des Moines, IA)
Assignee: ProdiGene, Inc. (College Station, TX)
Application Number:08/554,169
Patent Claims:see list of patent claims

Details for Patent 5,804,694

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial ProdiGene, Inc. (College Station, TX) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial ProdiGene, Inc. (College Station, TX) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial ProdiGene, Inc. (College Station, TX) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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