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Harvard Business School

Last Updated: October 1, 2020

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Patent: 5,795,891

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Summary for Patent: 5,795,891
Title: Acylphenylglycine derivative and preventive and remedy for diseases caused by increased collagenase activity containing said compound as active ingredient
Abstract:An acylphenylglycine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, and a preventive and remedy for diseases caused by an increased collagenase activity containing the same as the active ingredient, wherein R.sup.1 represents hydrogen atom, methyl, methylaminomethyl or morpholinomethyl; R.sup.2 represents hydrogen atom, hydroxy, fluorine atom, or C.sub.1 -C.sub.4 linear or branched alkyl; and R.sup.3 represents C.sub.1 -C.sub.4 linear or branched alkyl. The compound (I) and the salt maintains a potent collagenase inhibitor activity in the blood for long after being administered, and are useful as a remedy for various diseases believed to be caused by an increased collagenase activity. ##STR1##
Inventor(s): Hirayama; Ryoichi (Akashi, JP), Tsukida; Takahiro (Osaka, JP), Yamamoto; Minoru (Osaka, JP), Ikeda; Shoji (Kobe, JP), Sakamoto; Fumio (Daito, JP), Obata; Yuji (Osaka, JP), Matsuo; Konomi (Osaka, JP)
Assignee: Kanebo Ltd. (Tokyo, JP)
Application Number:08/596,278
Patent Claims:see list of patent claims

Details for Patent 5,795,891

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Kanebo Ltd. (Tokyo, JP) 2013-08-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Boehringer Ingelheim

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