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Generated: August 22, 2019

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Patent: 5,776,744

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Summary for Patent: 5,776,744
Title: Methods and compositions for effecting homologous recombination
Abstract:Methods, compositions and kits for effecting homologous recombination are described. In one aspect, the method utilizes two introduced DNAs: (1) a mutagen-linked single-stranded oligonucleotide capable of specifically binding to double-stranded DNA to form a triple-stranded helix, and (2) a donor DNA fragment capable of undergoing homologous recombination with DNA targeted by the oligonucleotide.
Inventor(s): Glazer; Peter M. (Guilford, CT), Lin; L. Michael (Wilmington, DE), George; Jay (Gaithersburg, MD)
Assignee: Yale University (New Haven, CT) Codon Pharmaceuticals, Inc. (Gaithersburg, MD)
Application Number:08/467,126
Patent Claims:see list of patent claims

Details for Patent 5,776,744

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Sign Up Yale University (New Haven, CT) Codon Pharmaceuticals, Inc. (Gaithersburg, MD) 2037-11-20 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Sign Up Yale University (New Haven, CT) Codon Pharmaceuticals, Inc. (Gaithersburg, MD) 2037-11-20 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Sign Up Yale University (New Haven, CT) Codon Pharmaceuticals, Inc. (Gaithersburg, MD) 2037-11-20 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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