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Generated: September 23, 2019

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Patent: 5,763,416

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Summary for Patent: 5,763,416
Title: Gene transfer into bone cells and tissues
Abstract:Disclosed are methods, compositions and devices for use in transferring nucleic acids into bone cells in situ. The transfer of an osteotropic gene into bone progenitor cells is described, which event is shown to stimulate the progenitor cells and to promote bone growth, repair and regeneration in vivo. These gene transfer protocols are suitable for use in transferring various nucleic acid materials into bone, and have many uses, for example, in treating various bone-related diseases and defects, such as, in promoting fracture repair, use in connection with implants, and in treating osteoporosis and osteogenesis imperfecta.
Inventor(s): Bonadio; Jeffrey (Ann Arbor, MI), Goldstein; Steven A. (Ann Arbor, MI)
Assignee: The Regent of the University of Michigan (Ann Arbor, MI)
Application Number:08/199,780
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 5,763,416
Patent Claims:see list of patent claims

Details for Patent 5,763,416

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23 ➤ Sign Up The Regent of the University of Michigan (Ann Arbor, MI) 2036-04-30 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23 ➤ Sign Up The Regent of the University of Michigan (Ann Arbor, MI) 2036-04-30 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23 ➤ Sign Up The Regent of the University of Michigan (Ann Arbor, MI) 2036-04-30 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23 ➤ Sign Up The Regent of the University of Michigan (Ann Arbor, MI) 2036-04-30 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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