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Last Updated: December 8, 2021

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Patent: 5,763,416

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Summary for Patent: 5,763,416
Title: Gene transfer into bone cells and tissues
Abstract:Disclosed are methods, compositions and devices for use in transferring nucleic acids into bone cells in situ. The transfer of an osteotropic gene into bone progenitor cells is described, which event is shown to stimulate the progenitor cells and to promote bone growth, repair and regeneration in vivo. These gene transfer protocols are suitable for use in transferring various nucleic acid materials into bone, and have many uses, for example, in treating various bone-related diseases and defects, such as, in promoting fracture repair, use in connection with implants, and in treating osteoporosis and osteogenesis imperfecta.
Inventor(s): Bonadio; Jeffrey (Ann Arbor, MI), Goldstein; Steven A. (Ann Arbor, MI)
Assignee: The Regent of the University of Michigan (Ann Arbor, MI)
Application Number:08/199,780
Patent Claims:see list of patent claims

Details for Patent 5,763,416

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Free Forever Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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