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Last Updated: December 1, 2021

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Patent: 5,760,019

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Summary for Patent: 5,760,019
Title: Silanol enzyme inhibitors
Abstract:Compounds of formula I ##STR1## in which X is OH Y is H, OH methyl or F, A and B are independently a) alkyl of one to ten carbons or heteroatoms, b) aryl of four to seven carbons or heteroatoms, c) cyclic of three to ten carbons or heteroatoms, or moieties of the formulas ##STR2## in a), b), c), d), e) and f), CH is bonded to silicon; R.sup.1 to R.sup.11 are independently hydrogen, alkyl of 1 to 10 carbons or heteroatoms, aryl of 4 to 14 carbons or heteroatoms, arylalkyl of 5 to 20 carbons or heteroatoms, substituted carbonyl or unsubstituted carbonyl; heteroatoms are nitrogen, oxygen, silicon or sulfur; and at least one of A and B is independently moieties d, e or f. The compounds of formula I inhibit protease enzymes and can be used as pharmaceuticals.
Inventor(s): Sieburth; Scott McN. (Coram, NY), Mutahi; Alfred M. (Edison, NJ)
Assignee: The Research Foundation of State University of New York (Albany, NY)
Application Number:08/680,330
Patent Claims:see list of patent claims

Details for Patent 5,760,019

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2039-03-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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