Methods and reagents for the identification and regulation of senescence-related genes
Identification of senescence-related genes can be accomplished by comparing mRNA expression between young and senescent cells. Probes complementary to such genes can be used to detect senescent cells and distinguish between young and senescent cells as well as in screens to identify compounds that alter expression levels of senescence-related genes.
Linskens; Maarten H. K. (Palo Alto, CA), Hirsch; Kenneth S. (Palo Alto, CA), Villeponteau; Bryant (San Carlos, CA), Feng; Junli (San Carlos, CA), Funk; Walter (Union City, CA), West; Michael David (Belmont, CA)
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