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Last Updated: March 24, 2023

Patent: 5,721,139

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Summary for Patent: 5,721,139
Title: Isolating and culturing schwann cells
Abstract:A method for enhancing the survival and/or proliferation of Schwann cells (especially human Schwann cells) in cell culture is disclosed which involves culturing the cells in serum free culture medium comprising gas6 and other mitogenic agents, such as heregulin and forskolin. The culturing step is generally preceded by a pre-incubation period wherein nerve tissue comprising the Schwann cells is cultured under appropriate conditions and for a period of time such that demyelination occurs. The isolated Schwann cells can be used as cellular prostheses to treat patients with nervous system injuries. The invention also provides a cell culture medium for culturing Schwann cells.
Inventor(s): Mather; Jennie P. (Millbrae, CA), Li; Ronghao (Millbrae, CA), Chen; Jian (Burlingame, CA)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:08/435,436
Patent Claims:see list of patent claims

Details for Patent 5,721,139

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 06/04/1965 See Plans and Pricing 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

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