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Last Updated: March 27, 2023

Patent: 5,717,084


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Summary for Patent: 5,717,084
Title: Chimaeric gene coding for a transit peptide and a heterologous peptide
Abstract:A chimaeric DNA sequence comprising: a) a nucleic acid sequence coding for a chimaeric protein or polypeptide comprising in sequence: 1) a transit peptide of a cytoplasmatic precursor of a chloroplast protein or polypeptide of a plant species, and, 2) a protein or polypeptide of interest which is different from a mature chloroplast protein or polypeptide contained in a natural cytoplasmatic precursor thereof, and, b) a promoter upstream of the nucleic acid sequence recognized by polymerases endogenous to a plant, whereby the chimaeric DNA sequence can be expressed in cells of the plant under the control of the promoter and the protein or polypeptide of interest can be translocated in the chloroplasts of the cells of the plant.
Inventor(s): Herrera-Estrella; Luis (Ghent, BE), Van Den Broeck; Guido (Ghent, BE), Van Montagu; Marc (Brussels, BE), Schreier; Peter (Cologne, DE), Schell; Jeff (Cologne, DE), Bohnert; Hans J. (Tucson, AZ), Cash more; Anthony R. (Woodside, NY), Timko; Michael P. (New York, NY), Kausch; Albert P. (Durham, NH)
Assignee: Plant Genetic Systems, N.V. (Brussels, BE) Bayer A.G. (Leverkusen, DE)
Application Number:08/470,719
Patent Claims:see list of patent claims

Details for Patent 5,717,084

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 See Plans and Pricing 2015-02-10
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 See Plans and Pricing 2015-02-10
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 See Plans and Pricing 2015-02-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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