Patent: 5,712,128

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Summary for Patent: 5,712,128

Title:	Enzymatic RNA molecules
Abstract:	Nucleic acid molecule having an RNA substrate cleaving enzymatic activity which cleaves a separate RNA substrate at a cleavage site. The nucleic acid molecule includes an RNA substrate binding portion which base pairs with the RNA substrate only 3\' of the cleavage site, and an enzymatic portion (which may include a part or all of the RNA substrate binding portion) having the enzymatic activity. The nucleic acid molecule is able to base pair with the RNA substrate only 3\' of the cleavage site, and cause cleavage of the RNA substrate at that cleavage site. The nucleic acid molecule can be either linear or circular. A general method for forming circular RNA in vivo and in vitro is provided.
Inventor(s):	Been; Michael D. (Durham, NC), Rosenstein; Sarah P. (Durham, NC), Perrotta; Anne T. (Garner, NC)
Assignee:	Duke University (Durham, NC)
Application Number:	08/434,453
Patent Claims:	see list of patent claims

Details for Patent 5,712,128

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Schering	INTRON A	interferon alfa-2b	VIAL	103132	003	1986-06-04	Start Trial	Duke University (Durham, NC)	2015-01-27	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	002	1986-06-04	Start Trial	Duke University (Durham, NC)	2015-01-27	RX		search
Schering	INTRON A	interferon alfa-2b	VIAL	103132	001	1986-06-04	Start Trial	Duke University (Durham, NC)	2015-01-27	RX		search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 5,712,128

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Country	Patent Number	Publication Date
World Intellectual Property Organization (WIPO)	9314218	Jul 22, 1993
United States of America	5625047	Apr 29, 1997
Japan	H07502898	Mar 30, 1995
European Patent Office	0623171	Feb 12, 1997
>Country	>Patent Number	>Publication Date

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