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Last Updated: September 28, 2020

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Patent: 5,677,282

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Summary for Patent: 5,677,282
Title: Amino acid amides of 1,3,4-thiadiazoles as matrix metalloproteinase
Abstract:Amino acid amides of 5-amino-1,3,4-thiadiazole-2-thione are disclosed. These compounds inhibit matrix metalloproteinase enzymes and cartilage degradation. Methods of treating diseases caused by over-activity of matrix metalloproteinases, such as osteoarthritis and rheumatoid arthritis, are also disclosed.
Inventor(s): Oleksyszyn; Jozef (Arlington, MA), Jacobson; Alan R. (Somerville, MA)
Assignee: Proscript, Inc. (Cambridge, MA)
Application Number:08/473,143
Patent Claims:see list of patent claims

Details for Patent 5,677,282

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Proscript, Inc. (Cambridge, MA) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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