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Last Updated: October 6, 2022

Patent: 5,674,722


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Summary for Patent: 5,674,722
Title: Genetic modification of endothelial cells
Abstract:Endothelial cells transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced endothelial cells are disclosed. Such endothelial cells are useful in improving the performance of vascular grafts and in delivering the encoded polypeptide or protein, such as an enzyme, a hormone, a receptor or a drug, to an individual.
Inventor(s): Mulligan; Richard C. (Lincoln, MA), Cohen; Lawrence K. (Oakland, CA), Rafield; Lori F. (San Fransisco, CA), Birinyi; Louis K. (Boston, MA), Callow; Allan D. (St. Louis, MO), Wilson; James M. (Ann Arbor, MI)
Assignee: Somatix Therapy Corporation (Alameda, CA) Whitehead Institute For Biomedical Research (Cambridge, MA) Brigham & Womens Hospital (Boston, MA) Howard Hughes Medical Institute (Bethesda, MD) New England Medical Center Hospitals (Boston, MA)
Application Number:08/249,092
Patent Claims:see list of patent claims

Details for Patent 5,674,722

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 01/23/2015 See Plans and Pricing 2014-10-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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