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Last Updated: December 3, 2021

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Patent: 5,667,985

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Summary for Patent: 5,667,985
Title: Tissue biopsy cell suspender for cell analysis
Abstract:A tissue biopsy cell suspender device includes a receptacle having a sealable opening. The receptacle contains a sufficient quantity of an aqueous medium to support an enzymatic dissociation of cells from a tissue biopsy sample. The device has a removable closure with a first sealing position and a second sealing position for sealing the opening in the receptacle. The device further includes a frangible container having a sufficient quantity of an enzyme therein to dissociate cells from the tissue biopsy sample. The frangible container is covered with a membrane that is permeable to water and to the enzyme. The frangible container is disposed within the receptacle so that the container is intact when the closure is in the first sealing position and the container is breached when the closure is in the second sealing position. When the frangible container is breached, the enzyme is released to permeate into the medium and for dissociation of the cells from the tissue sample.
Inventor(s): O\'Leary; Robert K. (Lexington, MA), Stevens; Timothy (Warwick, NY), Griffith; Richard L. (Allendale, NJ)
Assignee: Becton Dickinson and Company (Franklin Lakes, NJ)
Application Number:08/718,850
Patent Claims:see list of patent claims

Details for Patent 5,667,985

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Discure Medical, Llc CHYMODIACTIN chymopapain For Injection 018663 1982-11-10 ⤷  Try it Free 2039-03-29
Discure Medical, Llc CHYMODIACTIN chymopapain For Injection 018663 1984-08-21 ⤷  Try it Free 2039-03-29
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-05-05 ⤷  Try it Free 2039-03-29
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 2004-12-02 ⤷  Try it Free 2039-03-29
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 2004-10-26 ⤷  Try it Free 2039-03-29
Akorn, Inc. HYDASE hyaluronidase Injection 021716 2005-10-25 ⤷  Try it Free 2039-03-29
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2039-03-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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