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Last Updated: November 30, 2020

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Patent: 5,667,985

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Summary for Patent: 5,667,985
Title: Tissue biopsy cell suspender for cell analysis
Abstract:A tissue biopsy cell suspender device includes a receptacle having a sealable opening. The receptacle contains a sufficient quantity of an aqueous medium to support an enzymatic dissociation of cells from a tissue biopsy sample. The device has a removable closure with a first sealing position and a second sealing position for sealing the opening in the receptacle. The device further includes a frangible container having a sufficient quantity of an enzyme therein to dissociate cells from the tissue biopsy sample. The frangible container is covered with a membrane that is permeable to water and to the enzyme. The frangible container is disposed within the receptacle so that the container is intact when the closure is in the first sealing position and the container is breached when the closure is in the second sealing position. When the frangible container is breached, the enzyme is released to permeate into the medium and for dissociation of the cells from the tissue sample.
Inventor(s): O\'Leary; Robert K. (Lexington, MA), Stevens; Timothy (Warwick, NY), Griffith; Richard L. (Allendale, NJ)
Assignee: Becton Dickinson and Company (Franklin Lakes, NJ)
Application Number:08/718,850
Patent Claims:see list of patent claims

Details for Patent 5,667,985

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Discure Medical, Llc CHYMODIACTIN chymopapain INJECTABLE;INJECTION 018663 001 1984-07-09   Start Trial Becton Dickinson and Company (Franklin Lakes, NJ) 2039-03-29 DISCN search
Discure Medical, Llc CHYMODIACTIN chymopapain INJECTABLE;INJECTION 018663 002 1984-07-09   Start Trial Becton Dickinson and Company (Franklin Lakes, NJ) 2039-03-29 DISCN search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Becton Dickinson and Company (Franklin Lakes, NJ) 2039-03-29 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Becton Dickinson and Company (Franklin Lakes, NJ) 2039-03-29 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Becton Dickinson and Company (Franklin Lakes, NJ) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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