DrugPatentWatch Database Preview
Patent: 5,658,760
Summary for Patent: 5,658,760
| Title: | Heteropolymeric protein production methods |
| Abstract: | Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source. |
| Inventor(s): | Kelton; Christie A. (Hopkinton, MA), Nugent; Noreen P. (Framingham, MA), Chappel; Scott C. (Boston, MA) |
| Assignee: | Genzyme Corporation (Cambridge, MA) |
| Application Number: | 08/455,394 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 5,658,760 |
| Patent Claims: | see list of patent claims |
Details for Patent 5,658,760
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 001 | 1986-06-04 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 002 | 1986-06-04 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 003 | 1986-06-04 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
