DrugPatentWatch Database Preview
Patent: 5,658,760
» See Plans and Pricing
Summary for Patent: 5,658,760
| Title: | Heteropolymeric protein production methods |
| Abstract: | Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source. |
| Inventor(s): | Kelton; Christie A. (Hopkinton, MA), Nugent; Noreen P. (Framingham, MA), Chappel; Scott C. (Boston, MA) |
| Assignee: | Genzyme Corporation (Cambridge, MA) |
| Application Number: | 08/455,394 |
| Patent Claims: | see list of patent claims |
Details for Patent 5,658,760
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 003 | 1986-06-04 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 002 | 1986-06-04 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Schering | INTRON A | interferon alfa-2b | VIAL | 103132 | 001 | 1986-06-04 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Fresenius Kabi Usa | CHORIONIC GONADOTROPIN | gonadotropin, chorionic | INJECTABLE;INJECTION | 017067 | 004 | 1973-03-05 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Fresenius Kabi Usa | CHORIONIC GONADOTROPIN | gonadotropin, chorionic | INJECTABLE;INJECTION | 017067 | 003 | 1973-03-05 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Fresenius Kabi Usa | CHORIONIC GONADOTROPIN | gonadotropin, chorionic | INJECTABLE;INJECTION | 017067 | 002 | 1973-03-05 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| Fresenius Kabi Usa | CHORIONIC GONADOTROPIN | gonadotropin, chorionic | INJECTABLE;INJECTION | 017067 | 001 | 1973-03-05 | Start Trial | Genzyme Corporation (Cambridge, MA) | 2014-08-19 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 5,658,760
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| United States of America | 5240832 | Start Trial |
| United States of America | 5602006 | Start Trial |
| United States of America | 5674711 | Start Trial |
| Japan | 2001299374 | Start Trial |
| Japan | 3402604 | Start Trial |
| Japan | 3814156 | Start Trial |
| Japan | H0365194 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
