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Generated: August 24, 2019

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Patent: 5,650,554

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Summary for Patent: 5,650,554
Title: Oil-body proteins as carriers of high-value peptides in plants
Abstract:The present invention relates to the use of a class of genes called oil body protein genes that have unique features. The discovery of these features allowed the invention of methods for the production of recombinant proteins wherein a protein of interest can be easily separated from other host cell components. The invention is further exemplified by methods for exploitation of the unique characteristics of the oil body proteins and oil body genes for expression of polypeptides of interest in many organisms, particularly plant seeds. Said polypeptides may include but are not limited to: seed storage proteins, enzymes, bioactive peptides, antibodies and the like. The invention can also be modified to recover recombinant polypeptides fused to oleosins from non-plant host cells. Additionally the invention provides a method of using recombinant proteins associated with seed oil bodies released during seed germination for expression of polypeptides that afford protection to seedlings from pathogens. Finally, the persistent association of oil body proteins with the oil body can be further utilized to develop a biological means to create novel immobilized enzymes useful for bioconversion of substrates.
Inventor(s): Moloney; Maurice (Calgary, CA)
Assignee: SemBioSys Genetics Inc. (Calgary, CA)
Application Number:08/366,783
Patent Claims:see list of patent claims

Details for Patent 5,650,554

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Sign Up SemBioSys Genetics Inc. (Calgary, CA) 2014-07-22 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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International Patent Family for US Patent 5,650,554

Country Patent Number Publication Date
South Africa 9510999 Jul 13, 1996
World Intellectual Property Organization (WIPO) 9219989 Nov 12, 1992
World Intellectual Property Organization (WIPO) 9320216 Oct 14, 1993
World Intellectual Property Organization (WIPO) 9321320 Oct 28, 1993
World Intellectual Property Organization (WIPO) 9621029 Jul 11, 1996
>Country >Patent Number >Publication Date

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