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Last Updated: November 27, 2021

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Patent: 5,618,551

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Summary for Patent: 5,618,551
Title: Biocompatible bioresorbable and non-toxic adhesive composition for surgical use
Abstract:The invention relates to a biocompatible, bioresorbable and non-toxic adhesive composition for surgical use, for the bonding, in particular, of biological tissues to one another or in an implanted biomaterial, characterized in that it comprises a reactive acidic solution of non-crosslinked and potentially crosslinkable collagen or gelatin modified by oxidative cleavage, at a concentration which is preferably between approximately 5 and 30 by weight. It also relates to reactive acidic solutions and powders based on non-crosslinked collagen or gelatin modified by oxidative cleavage which are used as intermediate products in the preparation of the above-mentioned composition, and to the process for their preparation. It also relates to adhesive kits which comprise, on the one hand, the above-mentioned reactive acidic solution and, on the other hand, a neutralizing solution and which are intended for extemporaneous mixing. Finally it relates to a method of application of the adhesive, composition according to the invention. The invention is particularly useful in the areas of adhesion, haemostasis, leaktightness with respect to liquids or gases, cicatrization, filling, avoiding adhesion in surgery, embolization, as a local system for release of medicamentary active principles, etc.
Inventor(s): Tardy; Michel (Lyons, FR), Tiollier; J er ome (Lyons, FR), Tayot; Jean-Louis (La Tour De Salvagny, FR)
Assignee: Imedex (Chaponost, FR)
Application Number:08/376,185
Patent Claims:see list of patent claims

Details for Patent 5,618,551

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live For Injection 125123 2006-05-25 ⤷  Try it Free 2014-04-08
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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