cDNA-genomic DNA hybrid sequence encoding APP770 containing a genomic DNA insert of the KI and OX-2 regions
A nucleic acid construct is described which when expressed in cells, results in the production of APP695, APP751 and APP770. The construct is the cDNA for APP770 with the genomic sequences encoding the KI and OX-2 regions substituting for those regions present in the cDNA.
Wadsworth; Samuel (Shrewsbury, MA), Snyder; Benjamin (Worcester, MA), Reddy; Vermuri B. (Westborough, MA), Wei; Chamer (Westborough, MA)
Athena Neurosciences, Inc. (South San Francisco, CA)
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