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Generated: August 21, 2019

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Patent: 5,604,114

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Summary for Patent: 5,604,114
Title: Cis-acting repression sequences, cis-acting antirepression sequences, vectors, methods of preparation and use
Abstract:Cis-acting repression sequences which are able to provide a cis-acting inhibitory effect on the expression of a gene when placed downstream of the gene in its untranslated message are dislcosed. Cis-acting anti-repression sequences which can relieve the cis-acting repression in the presence of the art gene product are also disclosed. These sequences correspond to a sufficient number of nucleotides from the HIV-I, HIV-2, STLV-3 or HTLV-IV genomes to provide the repression or anti-repression effects. The use of the sequences in vectors and systems to control the expression of a desired gene product is also described.
Inventor(s): Haseltine; William A. (Cambridge, MA), Rosen; Craig A. (Glen Ridge, NJ), Sodroski; Joseph G. (Cambridge, MA), Terwilliger; Ernest (Boston, MA), Goh; Wei C. (Stanford, CA)
Assignee: Dana-Farber Cancer Institute (Boston, MA)
Application Number:08/041,887
Patent Claims:see list of patent claims

Details for Patent 5,604,114

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial Dana-Farber Cancer Institute (Boston, MA) 2014-02-18 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial Dana-Farber Cancer Institute (Boston, MA) 2014-02-18 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial Dana-Farber Cancer Institute (Boston, MA) 2014-02-18 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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