Synthesis of human procollagens and collagens in recombinant DNA systems
The invention is transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said collagen derived from said stable cell lines.
Prockop; Darwin J. (Philadelphia, PA), Ala-Kokko; Leena (Andalusia, PA), Fertala; Andrzej (Voorhees, NJ), Sieron; Aleksander (Conshohocken, PA), Kivirikko; Kari I. (Oulu, FI), Geddis; Amy (Philadelphia, PA), Pihlajaniemi; Taina (Oulunsalo, FI)
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