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Last Updated: July 11, 2020

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Patent: 5,580,776

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Summary for Patent: 5,580,776
Title: Modified hepatocytes and uses therefor
Abstract:Genetically engineered or transduced hepatocytes which express genetic material of interest introduced or incorporated into them, as well as methods of producing, transplanting and using the genetically engineered hepatocytes. The genetic material of interest can be incorporated through use of a vector, such as a recombinant retrovirus, which contains the genetic material of interest, or by other means.
Inventor(s): Wilson; James M. (Ann Arbor, MI), Mulligan; Richard C. (Cambridge, MA)
Assignee: Howard Hughes Medical Institute (Chevy Chase, MD) Whitehead Institute for Biomedical Research (Cambridge, MA)
Application Number:08/201,721
Patent Claims:see list of patent claims

Details for Patent 5,580,776

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Howard Hughes Medical Institute (Chevy Chase, MD) Whitehead Institute for Biomedical Research (Cambridge, MA) 2013-12-03 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Howard Hughes Medical Institute (Chevy Chase, MD) Whitehead Institute for Biomedical Research (Cambridge, MA) 2013-12-03 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Howard Hughes Medical Institute (Chevy Chase, MD) Whitehead Institute for Biomedical Research (Cambridge, MA) 2013-12-03 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Howard Hughes Medical Institute (Chevy Chase, MD) Whitehead Institute for Biomedical Research (Cambridge, MA) 2013-12-03 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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