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Generated: July 22, 2019

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Patent: 5,538,885

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Summary for Patent: 5,538,885
Title: Expression systems
Abstract:Expression systems which comprise a mammalian host, such as erythroid cells, transformed with a vector which comprises a promoter, a DNA sequence which codes for a desired polypeptide and a dominant control region. The vectors and methods for preparing polypeptides using the expression systems are also described. In a preferred embodiment, the vector contains cDNA for the desired polypeptide and a sequence which is capable of stabilising mRNA produced from the cDNA. The expression systems are particularly efficient and are capable of secreting the desired polypeptide.
Inventor(s): Hollis; Melvyn (Cheshire, GB2), Needham; Maurice R. C. (Cheshire, GB2), Gooding; Clare (Cheshire, GB2), Grosveld; Franklin G. (London, GB2), Antoniou; Michael (London, GB2)
Assignee: Imperial Chemical Industries PLC (London, GB)
Application Number:08/186,895
Patent Claims:see list of patent claims

Details for Patent 5,538,885

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Try a Free Trial Imperial Chemical Industries PLC (London, GB) ➤ Try a Free Trial RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Try a Free Trial Imperial Chemical Industries PLC (London, GB) ➤ Try a Free Trial RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Try a Free Trial Imperial Chemical Industries PLC (London, GB) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
Mallinckrodt
Johnson and Johnson
US Army
QuintilesIMS
Argus Health

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