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Last Updated: July 30, 2021

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Patent: 5,538,853

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Summary for Patent: 5,538,853
Title: Bone resorption assay based on a peptide liberated during collagen degradation
Abstract:An antibody raised to type I collagen carboxyterminal cross-linked telopeptide isolated from decalcified human or animal bone, may be used in an assay to determine the concentration of liberated carboxyterminal telopeptide region of the type I collagen molecule in a sample. When the sample is a body fluid such as serum or urine the degradation product measured is resistant to further degradation, since it contains a multivalent intermolecular cross-link, and can thus be found in the body fluid. The assay may be used to assess the degradation of type I collagen, the major organic constituent of bone matrix.
Inventor(s): Risteli; Juha P. (Oulu, FI), Risteli; Leila T. (Oulu, FI)
Assignee: Orion Corporation, Orion Diagnostica (Koivumankkaankuja, FI)
Application Number:08/274,105
Patent Claims:see list of patent claims

Details for Patent 5,538,853

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Free Forever Trial Orion Corporation, Orion Diagnostica (Koivumankkaankuja, FI) 2013-07-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Boehringer Ingelheim
Express Scripts

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