Patent: 5,538,853

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Summary for Patent: 5,538,853

Title:	Bone resorption assay based on a peptide liberated during collagen degradation
Abstract:	An antibody raised to type I collagen carboxyterminal cross-linked telopeptide isolated from decalcified human or animal bone, may be used in an assay to determine the concentration of liberated carboxyterminal telopeptide region of the type I collagen molecule in a sample. When the sample is a body fluid such as serum or urine the degradation product measured is resistant to further degradation, since it contains a multivalent intermolecular cross-link, and can thus be found in the body fluid. The assay may be used to assess the degradation of type I collagen, the major organic constituent of bone matrix.
Inventor(s):	Risteli; Juha P. (Oulu, FI), Risteli; Leila T. (Oulu, FI)
Assignee:	Orion Corporation, Orion Diagnostica (Koivumankkaankuja, FI)
Application Number:	08/274,105
Patent Claims:	see list of patent claims

Details for Patent 5,538,853

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	See Plans and Pricing	2013-07-23
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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