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Generated: August 24, 2019

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Patent: 5,491,130

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Summary for Patent: 5,491,130
Title: Peptide inhibitors of fibronectin and related collagen-binding proteins
Abstract:Peptides derived from the second type 1 repeat of human endothelial cell thrombospondin which bind to the gelatin-binding domain of fibronectin have been isolated and synthetically produced. The peptides can be used to bind to fibronectin or other related collagen-binding proteins to inhibit fibronectin-dependent cell adhesion to collagen matrices and to inhibit interactions with collagen of other proteins that share homologies with the gelatin-binding domain of fibronectin.
Inventor(s): Roberts; David D. (Bethesda, MD), Krutzsch; Henry C. (Bethesda, MD), Sipes; John M. (Cabin John, MD), Guo; Neng-hua (Gaithersburg, MD), Negre; Eric (Bethesda, MD)
Assignee: The United States of America as represented by the Department of Health (Washington, DC)
Application Number:07/973,235
Patent Claims:see list of patent claims

Details for Patent 5,491,130

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Sign Up The United States of America as represented by the Department of Health (Washington, DC) 2036-04-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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