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Last Updated: September 26, 2022

Patent: 5,457,092

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Summary for Patent: 5,457,092
Title: Methods of promoting bone growth in mammals comprising administration of modified parathyroid hormone
Abstract:pPTH, bPTH or hPTH is modified by deletions from the natural C- and/or N-terminus. The modified compounds are useful active ingredients in therapeutic compositions. The therapeutic compositions do not stimulate renal adenylate cyclase but, rather, effect chondrocyte proliferation, that is to say, they exhibit a mitogenic and bone-specific effect.
Inventor(s): Schluter; Klaus-Dieter (Braunschweig, DE), Mayer; Hubert (Braunschweig, DE), Wingender; Edgar (Braunschweig, DE)
Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF) (Braunschweig, DE)
Application Number:08/120,248
Patent Claims:see list of patent claims

Details for Patent 5,457,092

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 01/23/2015 See Plans and Pricing 2012-10-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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