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Generated: September 16, 2019

DrugPatentWatch Database Preview

Patent: 5,439,824

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Summary for Patent: 5,439,824
Title: Increased expression of .alpha.-1-antitrypsin in expression vectors through the inclusion of intron II
Abstract:The present invention relates to novel expression vectors and a method to increase the expression of .alpha..sub.1 -antitrypsin (AAT) from expression vectors encoding for the same through the inclusion of the Intron II sequence. Preferably, the Intron II sequence is included in its naturally occurring position, immediately after Exon II. Also, the invention is methods of therapy using the method and the expression vectors.
Inventor(s): Brantly; Mark (Silver Spring, MD), Laubach; Victor (Bethesda, MD)
Assignee: The United States of America (Washington, DC)
Application Number:08/060,925
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 5,439,824
Patent Claims:see list of patent claims

Details for Patent 5,439,824

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial The United States of America (Washington, DC) 2037-11-20 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial The United States of America (Washington, DC) 2037-11-20 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial The United States of America (Washington, DC) 2037-11-20 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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