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Generated: September 22, 2019

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Patent: 5,424,208

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Summary for Patent: 5,424,208
Title: Method for isolating cells from tissue with a composition containing collagenase and chymopapin
Abstract:Proteolytic enzyme compositions and processes for digesting connective tissue are provided. The enzyme compositions include collagenase, which is essentially free of toxins and non-collagen specific components, and chymopapain, which is essentially free of toxins. The enzyme compositions are used for dissociating microvessel cells from connective tissue. Recovered microvessel cells are incorporated into artificial vessel grafts. The composition preferrably contains collagenase having an activity of about 43 nkat/ml to about 51 nkat/ml and chymopapin having an activity of about 0.22 nkat/ml to about 0.44 nkat/ml.
Inventor(s): Lee; Catherine T. (Laguna Hills, CA), Hornacek; Cynthia (Trabuco Cyn, CA), Dinh; Tan T. (Garden Grove, CA)
Assignee: Baxter International Inc. (Deerfield, IL)
Application Number:08/311,383
Patent Claims:see list of patent claims

Details for Patent 5,424,208

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04   Try a Free Trial Baxter International Inc. (Deerfield, IL) 2013-04-16 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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