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Last Updated: March 24, 2023

Patent: 5,382,658

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Summary for Patent: 5,382,658
Title: Stability-enhanced variants of parathyroid hormone
Abstract:Herein described are variants of parathyroid hormone that retain significant PTH activity and are substantially resistant to trypsin and trypsin-like enzymes. The variants are useful pharmaceutically, to treat bone disorders such as osteoporosis and in other therapeutic applications. Specific embodiments of the invention include [His.sup.25 ]PTH and [His.sup.25 His.sup.26 Leu.sup.27 ]PTH.
Inventor(s): Kronis; K. Anne (Toronto, CA), Bozzato; Richard P. (Etobicoke, CA)
Assignee: Allelix Biopharmaceuticals Inc. (Mississauga, CA) Glaxo Canada Inc. (Mississauga, CA)
Application Number:07/863,014
Patent Claims:see list of patent claims

Details for Patent 5,382,658

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 01/23/2015 See Plans and Pricing 2039-03-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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