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Generated: September 18, 2019

DrugPatentWatch Database Preview

Patent: 5,366,859

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Summary for Patent: 5,366,859
Title: Radioimmunoassay method
Abstract:A radioimmunoassay which comprises the steps of reacting a first antibody (A) on an insoluble solid, which is specific for an antigen (B); an antigen (B); and a second antibody (C) derived from an animal different from that of the first antibody (A), which binds to the antigen (B) under conditions that the concentration of the second antibody (C) is higher than the dissociation constant between the second antibody (C) and the antigen (B) to obtain an immune complex (D); reacting the immune complex (D) with a radiolabeled probe (E) and then measuring the radioactivity of the solid precipitate or the reaction mixture, to measure the quantity of antigen (B). The method provides an assay with high sensitivity which does not depend on the sensitivity of the second antibody to be used.
Inventor(s): Miyoshi; Kinya (Ami, JP), Okada; Masato (Ami, JP), Takada; Makoto (Ami, JP), Goto; Mayumi (Ami, JP)
Assignee: Mitsubishi Petrochemical Co., Ltd. (Tokyo, JP)
Application Number:07/967,980
Patent Claims:see list of patent claims

Details for Patent 5,366,859

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Try a Free Trial Mitsubishi Petrochemical Co., Ltd. (Tokyo, JP) 2011-11-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Try a Free Trial Mitsubishi Petrochemical Co., Ltd. (Tokyo, JP) 2011-11-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Try a Free Trial Mitsubishi Petrochemical Co., Ltd. (Tokyo, JP) 2011-11-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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