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Last Updated: September 25, 2020

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Patent: 5,360,720

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Summary for Patent: 5,360,720
Title: Method of preparing human conjunctival mast cells for mast cell stabilization assays
Abstract:By allowing the mast cell enriched population of human conjunctival tissue cells to incubate for a minimum of about forty (40) hours post enzymatic digestion, the treatment window between spontaneous histamine release and anti-human IgE stimulated histamine release is increased. Culturing the human conjunctival tissue mast cells decreases the spontaneous release of histamine and increases the anti-IgE stimulated histamine release, greater than ten fold over spontaneous, at time points over forty (40) hours. This treatment window is sufficient to detect a compound\'s stabilizing or anti-allergic activity.
Inventor(s): Miller; Steven T. (Arlington, TX), Yanni; John M. (Burleson, TX)
Assignee: Alcon Laboratories, Inc. (Fort Worth, TX)
Application Number:08/134,148
Patent Claims:see list of patent claims

Details for Patent 5,360,720

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Alcon Laboratories, Inc. (Fort Worth, TX) 2039-02-26 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Alcon Laboratories, Inc. (Fort Worth, TX) 2039-02-26 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Alcon Laboratories, Inc. (Fort Worth, TX) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Merck
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Dow
Moodys
AstraZeneca

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