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Last Updated: September 20, 2020

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Patent: 5,352,778

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Summary for Patent: 5,352,778
Title: Recombinant thermostable DNA polymerase from archaebacteria
Abstract:Recombinant DNA polymeraset from archaebacteria as well as isolated DNA coding for such polymeraset are provided. The isolated DNA is obtained by use of DNA or antibody probet prepared from the DNA encoding T. litoralis DNA polymerate and the T. litoralis DNA polymerate respectively. Also provided are meshocs for producing recombinant archaebacteria thermostable DNA polymerase and methods for enhancing the expression of such polymeraset by identifying, locating and removing introns from within the DNA coding for such DNA polymerases.
Inventor(s): Comb; Donald G. (Beverly, MA), Perler; Francine (Brookline, MA), Kucera; Rebecca (Beverly, MA), Jack; William E. (Wenham, MA)
Assignee: New England Biolabs, Inc. (Beverly, MA)
Application Number:08/167,238
Patent Claims:see list of patent claims

Details for Patent 5,352,778

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial New England Biolabs, Inc. (Beverly, MA) 2010-04-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial New England Biolabs, Inc. (Beverly, MA) 2010-04-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial New England Biolabs, Inc. (Beverly, MA) 2010-04-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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