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Last Updated: June 9, 2023

Patent: 5,352,778

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Summary for Patent: 5,352,778
Title: Recombinant thermostable DNA polymerase from archaebacteria
Abstract:Recombinant DNA polymeraset from archaebacteria as well as isolated DNA coding for such polymeraset are provided. The isolated DNA is obtained by use of DNA or antibody probet prepared from the DNA encoding T. litoralis DNA polymerate and the T. litoralis DNA polymerate respectively. Also provided are meshocs for producing recombinant archaebacteria thermostable DNA polymerase and methods for enhancing the expression of such polymeraset by identifying, locating and removing introns from within the DNA coding for such DNA polymerases.
Inventor(s): Comb; Donald G. (Beverly, MA), Perler; Francine (Brookline, MA), Kucera; Rebecca (Beverly, MA), Jack; William E. (Wenham, MA)
Assignee: New England Biolabs, Inc. (Beverly, MA)
Application Number:08/167,238
Patent Claims:see list of patent claims

Details for Patent 5,352,778

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2010-04-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2010-04-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2010-04-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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