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Last Updated: December 8, 2021

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Patent: 5,276,137

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Summary for Patent: 5,276,137
Title: Analgesic peptides with a trifluoronorvaline modification
Abstract:The present invention relates to analgesic enkephalin derivatives represented by the following formula: and the acid salts thereof, wherein Tyr is L-tyrosine, A.sub.1 or A.sub.2 is a glycine, and that which is not a glycine is an optically active trifluoro amino acid of the formula: ##STR1## wherein n is an integer from 1-3 and m is 1 or 2; A.sub.3 is L-Phenylalanine, or N-methyl-(L)-phenylalanine, and A.sub.4 is L-Methionine, L-Met-OH, L-Met-ol or L-Met-NH.sub.2.
Inventor(s): Ojima; Iwao (Stony Brook, NY), Nakahashi; Kazuaki (Takaoka, JP)
Assignee: The Research Foundation of State University of New York (New York, NY)
Application Number:07/630,163
Patent Claims:see list of patent claims

Details for Patent 5,276,137

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live For Injection 125123 2006-05-25 ⤷  Free Forever Trial 2011-01-04
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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