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Last Updated: September 21, 2020

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Patent: 5,147,783

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Summary for Patent: 5,147,783
Title: Methods to screen for ovarian cancer and myocardial infarction
Abstract:A monoclonal antibody against human manganese-superoxide dismutase characterized in that it is produced by a cell line which has been obtained by immunization of a mouse with human Mn-SOD and then fusion of lymphocytes obtained from the mouse with mouse myeloma cells, and has high specificity against human Mn-SOD; a method for producing a monoclonal antibody against human Mn-SOD having high specificity against human Mn-SOD, which comprises culturing the cell line obtained by immunization of a mouse with human Mn-SOD and then cell fusion of lymphocytes obtained from the mouse with mouse myeloma cells; a kit for assaying human Mn-SOD, comprising: (a) a monoclonal antibody having very high specific immuno-reactivity against human Mn-SOD; and (b) a reagent of a monoclonal antibody having very high specific immuno-reactivity against human Mn-SOD labelled with an enzyme (enzyme labelled antibody); a method for assaying human Mn-SOD use of the kit; a novel diagnostic method of human epithelial ovarian cancer, which comprises assaying the concentration of human Mn-SOD in a body fluid by use of the assay kit; and a novel diagnostic method of myocardial infarction, which comprises assaying the concentration of human Mn-SOD in a body fluid by use of the assay kit.
Inventor(s): Uda; Taizo (Ube, JP), Itoh; Yukikatsu (Ube, JP), Kawaguchi; Tetsuo (Ube, JP), Hifumi; Emi (Ube, JP), Taniguchi; Naoyuki (Toyonaka, JP), Suzuki; Keiichiro (Takatsuki, JP), Ishikawa; Mutsuo (Asahikawa, JP), Noji; Shirou (Tokyo, JP)
Assignee: Ube Industries, Ltd. (Ube, JP)
Application Number:07/352,109
Patent Claims:see list of patent claims

Details for Patent 5,147,783

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Ube Industries, Ltd. (Ube, JP) 2009-09-15 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Ube Industries, Ltd. (Ube, JP) 2009-09-15 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Ube Industries, Ltd. (Ube, JP) 2009-09-15 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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