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Last Updated: September 28, 2020

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Patent: 5,139,944

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Summary for Patent: 5,139,944
Title: Collagen-specific enzyme with platelet aggregation inhibition properties
Abstract:The collagenase is like tissue collagenases in that it cleaves collagen at a single site. The collagenase which has a molecular weight of about 50 k daltons, specifically inhibits collagen-induced platelet aggregation, with substantially no effect on platelet count or size, and may be used alone or together with another platelet aggregation inhibitor. The latter may also be a leech-derived biochemical, such as an apyrase, or an inhibitor of the release of platelet aggregation factor by leucocytes.
Inventor(s): Sawyer; Roy T. (Swansea, GB), Rigbi; Meir (Jerusalem, IL), Levy; Haim (Jerusalem, IL), Iraqi; Fuad (Jerusalem, IL)
Assignee: Biophram (UK) Limited (West Glamorgan, GB) Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, IL)
Application Number:07/647,652
Patent Claims:see list of patent claims

Details for Patent 5,139,944

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Biophram (UK) Limited (West Glamorgan, GB) Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, IL) 2009-08-18 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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