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Last Updated: June 29, 2022

Patent: 5,137,669

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Summary for Patent: 5,137,669
Title: Manufacture of partially fused peptide pellet
Abstract:A bioerodible pellet capable of administering an even and continuous dose of a peptide over a period of up to a year, when subcutaneously implanted, is provided. The bioerodible implant is a partially-fused pellet, which pellet has a peptide drug homogeneously-bound in a matrix of a melted and recrystallized, nonpolymer carrier. Preferably, the nonpolymer carrier is a steroid and in particular is cholesterol or a cholesterol derivative. In one embodiment, the peptide drug is growth hormone-releasing hormone. A method for making the bioerodible pellet also is provided.
Inventor(s): Leonard; Robert J. (Lynnfield, MA), Harman; S. Mitchell (Ellicott City, MD)
Assignee: Endocon, Inc. (South Walpole, MA)
Application Number:07/695,924
Patent Claims:see list of patent claims

Details for Patent 5,137,669

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 01/23/2015 See Plans and Pricing 2009-08-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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