Patent: 5,137,669
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Summary for Patent: 5,137,669
| Title: | Manufacture of partially fused peptide pellet |
| Abstract: | A bioerodible pellet capable of administering an even and continuous dose of a peptide over a period of up to a year, when subcutaneously implanted, is provided. The bioerodible implant is a partially-fused pellet, which pellet has a peptide drug homogeneously-bound in a matrix of a melted and recrystallized, nonpolymer carrier. Preferably, the nonpolymer carrier is a steroid and in particular is cholesterol or a cholesterol derivative. In one embodiment, the peptide drug is growth hormone-releasing hormone. A method for making the bioerodible pellet also is provided. |
| Inventor(s): | Leonard; Robert J. (Lynnfield, MA), Harman; S. Mitchell (Ellicott City, MD) |
| Assignee: | Endocon, Inc. (South Walpole, MA) |
| Application Number: | 07/695,924 |
| Patent Claims: | see list of patent claims |
Details for Patent 5,137,669
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Nps Pharmaceuticals, Inc. | NATPARA | parathyroid hormone | For Injection | 125511 | 01/23/2015 | See Plans and Pricing | 2009-08-11 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
