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Patent: 5,137,669
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Summary for Patent: 5,137,669
Title: | Manufacture of partially fused peptide pellet |
Abstract: | A bioerodible pellet capable of administering an even and continuous dose of a peptide over a period of up to a year, when subcutaneously implanted, is provided. The bioerodible implant is a partially-fused pellet, which pellet has a peptide drug homogeneously-bound in a matrix of a melted and recrystallized, nonpolymer carrier. Preferably, the nonpolymer carrier is a steroid and in particular is cholesterol or a cholesterol derivative. In one embodiment, the peptide drug is growth hormone-releasing hormone. A method for making the bioerodible pellet also is provided. |
Inventor(s): | Leonard; Robert J. (Lynnfield, MA), Harman; S. Mitchell (Ellicott City, MD) |
Assignee: | Endocon, Inc. (South Walpole, MA) |
Application Number: | 07/695,924 |
Patent Claims: | see list of patent claims |
Details for Patent 5,137,669
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 004 | 2015-01-23 | Start Trial | Endocon, Inc. (South Walpole, MA) | 2009-08-11 | RX | Orphan | search |
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 003 | 2015-01-23 | Start Trial | Endocon, Inc. (South Walpole, MA) | 2009-08-11 | RX | Orphan | search |
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 002 | 2015-01-23 | Start Trial | Endocon, Inc. (South Walpole, MA) | 2009-08-11 | RX | Orphan | search |
Nps Pharms Inc | NATPARA | parathyroid hormone | INJECTABLE;INJECTION | 125511 | 001 | 2015-01-23 | Start Trial | Endocon, Inc. (South Walpole, MA) | 2009-08-11 | RX | Orphan | search |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 5,137,669
Country | Patent Number | Estimated Expiration |
---|---|---|
United States of America | 5039660 | Start Trial |
>Country | >Patent Number | >Estimated Expiration |