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Last Updated: February 19, 2020

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Patent: 5,137,669

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Summary for Patent: 5,137,669

Title:	Manufacture of partially fused peptide pellet
Abstract:	A bioerodible pellet capable of administering an even and continuous dose of a peptide over a period of up to a year, when subcutaneously implanted, is provided. The bioerodible implant is a partially-fused pellet, which pellet has a peptide drug homogeneously-bound in a matrix of a melted and recrystallized, nonpolymer carrier. Preferably, the nonpolymer carrier is a steroid and in particular is cholesterol or a cholesterol derivative. In one embodiment, the peptide drug is growth hormone-releasing hormone. A method for making the bioerodible pellet also is provided.
Inventor(s):	Leonard; Robert J. (Lynnfield, MA), Harman; S. Mitchell (Ellicott City, MD)
Assignee:	Endocon, Inc. (South Walpole, MA)
Application Number:	07/695,924
Patent Claims:	see list of patent claims

Details for Patent 5,137,669

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	001	2015-01-23	Start Trial	Endocon, Inc. (South Walpole, MA)	2009-08-11	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	002	2015-01-23	Start Trial	Endocon, Inc. (South Walpole, MA)	2009-08-11	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	003	2015-01-23	Start Trial	Endocon, Inc. (South Walpole, MA)	2009-08-11	RX	Orphan	search
Nps Pharms Inc	NATPARA	parathyroid hormone	INJECTABLE;INJECTION	125511	004	2015-01-23	Start Trial	Endocon, Inc. (South Walpole, MA)	2009-08-11	RX	Orphan	search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 5,137,669

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Country	Patent Number	Publication Date
United States of America	5039660	Aug 13, 1991
>Country	>Patent Number	>Publication Date

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